faculty profile

Marianna LaNoue   PhD



Dr. LaNoue is an experimental psychologist, research methodologist and biostatistician. She has a strong record of collaborative research and research leadership, particularly in health services and outcomes research. Her current interests include the methods of patient-centered outcomes research (PCOR), particularly the development and testing of patient engagement evaluation approaches.

She maintains a strong interest in assessment of adverse childhood experiences, specifically the evaluation of assessment strategies and measurement models for childhood trauma.

Dr. LaNoue joined VUSM in 2021 after 10 years at Thomas Jefferson University in the colleges of Medicine and Population Health where she held multiple positions in research capacity development & infrastructure building, and research leadership.


  • PhD, Experimental Psychology/Quantitative Methods, University of New Mexico
  • MS, Psychology, University of New Mexico
  • BS, Psychology, University of New Mexico/University of Hawaii

Current Research/Scholarly Interests

1. Assessment of Childhood Adversity

A very large body of research documents relationships between self-reported Adverse Childhood Experiences (ACEs) and adult health outcomes. Despite multiple assessment tools that use the same or similar questions (such as those in the CDC's 'Behavioral Risk Factor Surveillance System - BRFSS assessment), there is very little foundational research into alternative assessment strategies and a great deal of inconsistency in the operationalization of self-reported childhood adversity for use as a predictor variable. Alternative conceptual models to the cumulative ACE Score are rarely used and very limited evidence directly contrasts conceptual models to each other. Dr. LaNoue's research investigates the statistical and measurement properties of ACE assessments.

2. Methods of Patient Centered Outcomes Research

Despite national focus on the importance of patient-centered research and clinical care delivery, many researchers and clinicians use endpoints that they presume to be important to patients rather than directly engaging patients to identify patient-important outcomes (PIOs). PIOs are outcomes that take into account individual patient values and preferences and are grounded in patient values and preferences. Dr. LaNoue's research in this space focuses on strategies for engaging patients in the research process with an emphasis on the implementation of the group concept mapping (GCM) method) and measuring the outcomes of patient-engagement.


Completed Grant Support

Children's Investment Fund Foundation (CIFF)
Title: Reducing Anemia in Pregnancy in India: The RAPID-IRON Trial
Project Period: 05/2020-04/2024
Role: Co-I

Foundation for Opioid Response Efforts (FORE Foundation)
Title: Lowering Barriers, Saving Lives, Reclaiming Health: Integrating MAT
Project Period: 02/2020-02/2022
Role: Co-I

American Association of Colleges of Osteopathic Medicine (AACOM)
Title: Phase 2 - Project in Osteopathic Medicine and Empathy (POME): Longitudinal Study of Changes in Empathy in Medical School.
Project Period: 06/17/2019- 06/30/2024
Role: Co-I

080-31050-U08101 Patient-Centered Outcomes Research Institute (PCORI)
Title: Concept Mapping as a Scalable Method for Identifying Patient-Important Outcomes.
http://www.pcori.org/research-results/2015/concept-mapping-scalable-method-identifying-patient-important-outcomes. Project Period: 01/2016-12/2018
Role: Co-Principal Investigator

080-31050-U09201 Emergency Medicine Foundation/Emergency Nursing Association (EMF/ENA)
Title: Measuring Patient Uncertainty During Acute Care.
Project Period: 7/1/2016-6/30/2017
Role: Co-Investigator

RS-15-006 The Gold Foundation for Humanism in Medicine
Title: Evaluating Dimensions of Patient-Centeredness. PI: M. LaNoue, PhD
Project Period: 07/01/2015 - 06/30/2016
Role: PI

Representative Publications


1. Assessment of Childhood Adversity

LaNoue, MD, George, BG, Keith, SK, Helitzer, DL. Contrasting Cumulative Risk and Multiple Individual Risk Models of the Relationship Between Adverse Childhood Experiences (ACEs) and Adult Health Outcomes BMC Medical Research Methodology 2020 20:239

Gannon, MA, Short, VL, LaNoue, MD, Abatemarco, DA. Prevalence of Adverse Childhood Experiences of Parenting Women in Drug Treatment for Opioid Use Disorder. Community Mental Health Journal (2020), DOI: https://doi.org/10.1007/s10597-020-00661-0).

LaNoue MD, Cunningham, A.T., Abatemarco, D.A., Helitzer, D.L. What do adults think about their adverse childhood experiences (ACEs), and does it matter? Community Mental Health Journal : 2020, 51(7), 768-774. https://doi.org/10.1007/s10597-020-00580-0

2. Methods of Patient Centered Outcomes Research

Rising KL, LaNoue MD, Gentsch AG, Doty AMB, Cunningham AT, Mills GD., et al. The Power of the Group: Comparison of interviews and group concept mapping for identifying patient-important outcomes of care. BMC Medical Research Methodology. 2019: https://doi.org/10.1186/s12874-018-0656-x

LaNoue MD, Cunningham AT, Gentsch AG, Doty AMB, Mills GD, Rising KL. Eliciting Patient-Important Outcomes Through Group Brainstorming: When is Saturation Reached? Journal of Patient-Reported Outcomes. 2018:3(9). https://doi.org/10.1186/s41687-019-0097-2

Rising KL, Gerolamo A, Powell RH, Doyle S & LaNoue MD. Use of Group Concept Mapping to Identify Patient Domains of Uncertainty That Contribute to Emergency Department Use. Journal of Emergency Nursing, 2018: https://doi.org/10.1016/j.jen.2018.05.015

LaNoue MD, Mills GD, Cunningham AT, Sharbaugh A. Concept Mapping as a Method to Engage Patients in Clinical Quality Improvement. Annals of Family Medicine. 2016:14(4), 370-376. doi: 10.1370/afm.1929

Mills GD, LaNoue MD, Gentsch AT, Doty AMB, Cunningham A, Nord G, Rising KL. Patient experience and challenges in group concept mapping for clinical research. Journal of Patient-Reported Outcomes. 2019 15;3(1):54. doi: 10.1186/s41687-019-0147-9.


  • Editorial Board Member (Statistical Reviewer), BMC Health Services Research
  • Editorial Board Member (Statistical Reviewer), BMC Medical Education

Peer reviews are indexed at www.publons.com/author/485820/marianna-lanoue

Professional Organizations

  • International Society for Quality of Life Research (ISOQOL)
  • Academy Health
  • American Psychological Association, Division 38 (Society for Health Psychology) & Division 3 (Quantitative Methods)


  • 2020 - Provost's Team Award for Interdisciplinary Research, Thomas Jefferson University
  • 2019 - Award for Outstanding Teaching, Thomas Jefferson University
  • 2018 - Editorial Recognition for High Quality Peer Review, American Journal of Preventive Medicine
  • 2017 - Dean's Award for Excellence in Faculty Mentoring, Sidney Kimmel Medical College
  • 2016 - "Sentinels of Science: Medicine" Peer Review Recognition, Publons.com
  • 2015 - Marjorie K Bowman Early Career Investigator Award, Sidney Kimmel Medical College
  • 2014 - Faculty Team Achievement Award, DFCM Chronic Care Initiative. Sidney Kimmel Medical College
  • 2006 - Ph.D. Awarded with distinction
  • 1999 - Summa Cum Laude in Psychology, Magna Cum Laude (BS), University of New Mexico